dasatinib will boost the degree or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
cenobamate will improve the amount or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Watch Closely. Contemplate a dose reduction of CYP2C19 substrates, as clinically correct, when used concomitantly with cenobamate.
Es posible que su médico necesite cambiar las dosis de sus medicamentos y que lo mantenga bajo una cuidadosa supervisión. Si United states of america el diazepam con cualquiera de estos medicamentos y desarrolla cualquiera de los siguientes síntomas, llame a su médico o busque atención médica de emergencia inmediatamente: mareos inusuales, aturdimiento, somnolencia extrema, respiración lenta o dificultosa o falta de capacidad de respuesta. Asegúrese de que su cuidador o sus familiares sepan qué síntomas pueden ser graves para que puedan llamar al médico o a un servicio de urgencias si usted no puede buscar tratamiento por sí mismo.
istradefylline will raise the degree or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
informe a su médico si está embarazada o si tiene planes de quedar embarazada. Llame a su médico de inmediato si queda embarazada mientras toma diazepam.
Concomitant usage of benzodiazepines, together with diazepam, and opioids could end in profound sedation, respiratory depression, coma, and Loss of life; reserve concomitant prescribing of benzodiazepines and opioids to be used in patients for whom option remedy selections are insufficient; reduce opiate dose one particular-third when diazepam is added
Threat of Misuse and Habit. Misusing diazepam may lead to severe side effects like coma or Loss of life. Misuse suggests using a medicine in a way in addition to how it was prescribed.
buprenorphine, lengthy-performing injection and diazepam both boost sedation. Stay away from or Use Alternate Drug. Limit use to patients for whom option remedy solutions are insufficient
Oral Remedy. Use an exact measuring gadget to measure your dose. A household spoon is just not an correct measuring product and could trigger you to choose the wrong dose. Talk to your pharmacist to endorse an ideal measuring gadget.
The benzodiazepines acquired popularity among medical professionals being an enhancement above barbiturates, which have a relatively narrow therapeutic index, and are considerably more sedative at therapeutic doses. The benzodiazepines also are much much less risky; Loss of life not often outcomes from diazepam overdose, other than in conditions the place it is actually eaten with big amounts of other depressants (for instance Alcoholic beverages or opioids).
Coadministration of other CNS depressants or Liquor usage may possibly potentiate CNS-depressant consequences of diazepam
Medicine that have quantity boundaries connected to Each individual prescription. This restriction usually limitations the quantity in the drug that may be here included.
methylprednisolone will lower the extent or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
prednisone will reduce the level or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.